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Pregnancy with Rheumatoid Arthritis–before you plan pregnancy

Methotrexate—This drug may remain in the liver upto 100–120 days. Hence, it should be stopped at least 3–4 months prior to cocnception to avoid potential risk to the unborn baby. You should be taking folic acid during this period and should continue taking it thereafter.

Leflunomide—This drug remains in the system for as long as 3 years. If you are on Leflunomide and plan to conceive, you need a wash out therapy. The same includes a drug called cholestyramine to be taken for 11 days to wash out leflunomide from the body. You should plan pregnancy 3 months after the wash out therapy.

Sulphasalazine—is considered safe in pregnancy and need not be stopped.

Hydroxychloroquine—is considered safe in pregnancy.

Do consult your Rheumatologist before you plan to conceive for the necessary changes in your anti—arthritis drugs.

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Also Read:
Pregnancy with Rheumatoid Arthritis
Which of the anti–arthritis drugs are safe in pregnancy?
Which of the anti–arthrtis drugs are safe while breast feeding the baby?
Do anti–arhritis drugs affect fertility?
I am a man with Rheumatoid arthritis, what precautions should I take before planning a family?
Are biologicals safe in pregnancy?

Created on: April 2007
Last updated on: Feb 2015
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